Lehninger Principles of Biochemistry
David L. Nelson, Michael M. Cox
Language: English
Pages: 1340
ISBN: 1429234148
Format: PDF / Kindle (mobi) / ePub
Clear writing and illustrations…Clear explanations of difficult concepts…Clear communication of the ways in biochemistry is currently understood and practiced. For over 35 years, in edition after bestselling edition, Principles of Biochemistry has put those defining principles into practice, guiding students through a coherent introduction to the essentials of biochemistry without overwhelming them.
The new edition brings this remarkable text into a new era. Like its predecessors, Lehninger Principles of Biochemistry, Sixth Edition strikes a careful balance of current science and enduring concepts, incorporating a tremendous amount of new findings, but only those that help illustrate biochemistry’s foundational principles. With this edition, students will encounter new information emerging from high throughput DNA sequencing, x-ray crystallography, and the manipulation of genes and gene expression, and other techniques. In addition, students will see how contemporary biochemistry has shifted away from exploring metabolic pathways in isolation to focusing on interactions among pathways. They will also get an updated understanding of the relevance of biochemistry to the study of human disease (especially diabetes) as well as the important role of evolutionary theory in biochemical research.
These extensive content changes, as well as new art and powerful new learning technologies make this edition of Lehninger Principles of Biochemistry the most impressive yet.
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Into Sheets Protein Architecture— Sheet In 1951, Pauling and Corey predicted a second type of repetitive structure, the  conformation. This is a more extended conformation of polypeptide chains, and its structure is again defined by backbone atoms arranged according to a characteristic set of dihedral angles (Table 4–1). In the  conformation, the backbone of the polypeptide chain is extended into a zigzag rather than helical structure (Fig. 4–6). The arrangement of several segments side by.
By Jane Richardson, which highlights regions of secondary structure. The ␣-helical regions are evident. (b) Surface contour (a four-character identifier called the PDB ID). Such labels are provided in the figure legends for every PDBderived structure illustrated in this text so that students and instructors can explore the same structures on their own. The data files in the PDB describe the spatial coordinates of each atom whose position has been determined (many of the cataloged structures are.
Kitchen (i.e., the “universe”) but has become completely randomized throughout. This The Flow of Electrons Provides Energy for Organisms Nearly all living organisms derive their energy, directly or indirectly, from the radiant energy of sunlight. In the photoautotrophs, light-driven splitting of water during photosynthesis releases its electrons for the reduction of CO2 and the release of O2 into the atmosphere: light 6CO2 ϩ 6H2O 888n C6H12O6 ϩ 6O2 (light-driven reduction of CO2).
Space-filling dimensions of atoms. When two atoms are joined covalently, the atomic radii at the point of bonding are less than the van der Waals radii, because the joined atoms are pulled together by the shared electron pair. The distance between nuclei in a van der Waals interaction or a covalent bond is about equal to the sum of the van der Waals or covalent radii, respectively, for the two atoms. Thus the length of a carbon–carbon single bond is about 0.077 nm 1 0.077 nm 5 0.154 nm.
E.S., Cayley, D.S., & Guttman, H.J. (1998) Responses of E. coli to osmotic stress: large changes in amounts of cytoplasmic solutes and water. Trends Biochem. Sci. 23, 143–148. Intermediate-level review of the ways in which a bacterial cell counters changes in the osmolarity of its surroundings. (See also Cayley et al., 2000, above.) Denny, M.W. (1993) Air and Water: The Biology and Physics of Life’s Media, Princeton University Press, Princeton, NJ. A wonderful investigation of the biological.