Hormone/Behavior Relations of Clinical Importance: Endocrine Systems Interacting with Brain and Behavior
Robert T. Rubin, Donald W. Pfaff, M. Ian Phillips
Language: English
Pages: 355
ISBN: 2:00270583
Format: PDF / Kindle (mobi) / ePub
Publish Year note: First published in 2004. Material in this work originally appeared in Hormones, Brain and Behavior, 2nd Edition published in 2002.
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A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2nd Edition MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009).
The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.
• Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented)
• Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
• Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader
• Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders)
• Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists
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Or retained some female gender identity. The outward switch of sex and gender identity from female to male at puberty in 5-alpha-reductase-deficient individuals was initially interpreted as the primacy of nature over nurture; that is, sex hormones are more influential than psychosocial factors imposed since infancy. However, despite the early recognition that newborns from affected families and with ambiguous genitalia might have masculine pubertal development, these infants have been raised.
Temporal envelope of its concentration, but also the sensitivity of the cellular response to the hormone. This is mediated by specific receptors that detect and bind to the hormone and then signal to the cell over a variety of pathways, thus shaping the response of the cell. Therefore, determining optimal levels for a given hormone must be done keeping all of these mechanistic steps in mind. I. TOO MUCH To begin with a subtle example, it is possible to have the appearance of too much hormone but.
Males are more aggressive than females, in a variety of species and under a variety of circumstances. Both androgenic hormones (e.g., testosterone) and estrogenic hormones play a role in facilitating aggression. Among men, bodybuilders taking androgens of high potency to build muscles are storied, anecdotally, for occasional hostile acts known as ‘‘roid rage’’ (see Chapter 5). In the normal case, however, aggression in animals and humans does not occur in the absence of provocative stimuli from.
The importance of how the child is treated by parents and other adults in determining whether the child eventually feels and acts like a man or a woman. ‘‘Sex of rearing’’ was thought of as being an important factor. In sum, despite the fact that biochemical versus behavioral influences have historically been portrayed as opposing camps in medical science, they are not mutually exclusive. The incidence of major depression is twice as great in adult women as in adult men. Prior to puberty, the.
Postpubertal woman and man, compared to the girl and boy, respectively. (From Clark et al., 1997.) 150 Puberty Alters Hormone Secretion and Hormone Responsivity FIGURE 10.3. Premature activation of the hypothalamicÀpituitaryÀtesticular axis in immature male rhesus monkeys induced by repetitive stimulation of the hypothalamus with NMDA, an excitatory amino acid receptor agonist, administered once every 3 hours for 15 weeks. The treatment was initiated 1.5À2 years before the normal age of.